Stereocontrolled syntheses of polyhydroxy indolizidines, including 8a-epi-, 6,8a-diepi- and 1,6-diepi-castanospermine, starting from malic acid

DOI: 10.1016/0040-4039(95)00249-C

Source and publish data:

Tetrahedron Letters p. 2335 - 2338 (1995)

Update date:2022-09-26

Topics:

Authors:

Leeper, Finian J.

Howard, Steven

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Article abstract of DOI:10.1016/0040-4039(95)00249-C

Stereocontrolled total syntheses of one trihydroxy indolizidine 15 and three tetrahydroxy indolizidines, 17, 21 and 23 - all diastereoisomers of castanospermine - are described which use malic acid as the only chiral starting material.

Full text of DOI:10.1016/0040-4039(95)00249-C

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