Stereocontrolled syntheses of polyhydroxy indolizidines, including 8a-epi-, 6,8a-diepi- and 1,6-diepi-castanospermine, starting from malic acid

Article abstract of DOI:10.1016/0040-4039(95)00249-C

Stereocontrolled total syntheses of one trihydroxy indolizidine 15 and three tetrahydroxy indolizidines, 17, 21 and 23 - all diastereoisomers of castanospermine - are described which use malic acid as the only chiral starting material.