Indium-catalyzed hydroamination/hydrosilylation of terminal alkynes and aromatic amines through a one-pot, two-step protocol

DOI: 10.1002/ejoc.201402544

Source and publish data:

European Journal of Organic Chemistry p. 5078 - 5082 (2014)

Update date:2022-08-05

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Authors:

Sakai, Norio

Takahashi, Nobuaki

Ogiwara, Yohei

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Article abstract of DOI:10.1002/ejoc.201402544

We demonstrated that indium tribromide effectively functioned as a single catalyst for two successive steps in a one-pot procedure. First, the hydroamination of alkynes with anilines took place to give the Markovnikov product. Then, hydrosilylation of the imine intermediates by treatment with a hydrosilane substrate afforded the corresponding secondary amines.

Full text of DOI:10.1002/ejoc.201402544

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