Synthesis of New α,α-Difluoro-γ-lactones through Intramolecular Radical Cyclization as a Key Reaction

Article abstract of DOI:10.1016/0040-4039(95)00518-H

Carbon radicals from allyl o-trimethylsilyl-α-bromo-α,α-difluoroacetals can cyclize onto olefines regiospecifically to give γ-lactols in good yield.These lactols have been converted to the corresponding α,α-difluoro-γ-lactones.The first synthesis of three