Journal of Medicinal Chemistry p. 2263 - 2267 (1995)
Update date:2022-07-30
Topics:
Chen
Fairchild
Long
Three novel C-4 aziridine-bearing paclitaxel analogs, 3-5, have been synthesized during the course of our continuing effort at C-4 modification. The key step in the synthesis is the aziridine ring formation at the C-4 position via an intramolecular Mitsun
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