Synthesis of 6-amino-1-benzyl-4-methylhexahydro-1H-1,4-diazepine

DOI: 10.1002/jhet.5570320244

Source and publish data:

Journal of Heterocyclic Chemistry p. 637 - 642 (1995)

Update date:2022-08-03

Topics: Characterization Hydrogenation Purification Reductive Amination Deprotection of Amine

Authors:

Kato Kato

Harada Harada

Morie Morie

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Article abstract of DOI:10.1002/jhet.5570320244

Five variants (methods A-E) of a synthetic route to 6-amino-1-benzyl-4-methylhexahydro-1H-1,4-diazepine (3b) using N-benzyl-N'-methylethylenediamine (8a) are described. The reaction of 8a with 1 benzenesulfonyl-2-bromomethylaziridine (7), 2-phenyl-4-(p-to

Full text of DOI:10.1002/jhet.5570320244

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