Tetrahedron Letters p. 5183 - 5186 (1995)
Update date:2022-08-05
Topics:
Saady, Mourad
Lebeau, Luc
Mioskowski, Charles
For the first time, benzyl phosphites allowed the preparation of a set of polyphosphonates from chloromethyl halides via the Michaelis-Arbuzov reaction performed under vacuum.Regioselective mono-deprotection or complete deprotection of these phosphonates provide useful building blocks for the synthesis of biological phosphate analogs.
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