Synthesis and biological evaluation of some acyclic pyridine C- nucleosides. Part one

Article abstract of DOI:10.1080/15257779408013225

The reaction between 3-bromo-5-chloromethylpyridine hydrochloride (4) with the mono sodium salt of ethylene glycol was investigated. 3-Bromo-5-(2- hydroxyethoxymethyl)-pyridine (5) was synthesized and converted to the 3- carboxy analogue using butyllithiu

Full text of DOI:10.1080/15257779408013225

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Nucleosides and Nucleotides
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Synthesis and Biological Evaluation of
Some Acyclic Pyridine C-Nucleosides.
Part One
J. Van Hemel a , E. L. Esmans a , F. C. Alderweireldt a , R. A.
Dommisse a , A. De Groot a , J. Balzarini b & E. De Clercq b
a University of Antwerp (RUCA), Nucleoside Research
Groenenborgerlaan , 171, B-2020, Antwerp, BELGIUM
b University of Leuven, Rega Institute for Medical Research
Minderbroedersstraat 10 , B-3000, Leuven, BELGIUM
Published online: 24 Sep 2006.
To cite this article: J. Van Hemel , E. L. Esmans , F. C. Alderweireldt , R. A. Dommisse , A.
De Groot , J. Balzarini & E. De Clercq (1994) Synthesis and Biological Evaluation of Some
Acyclic Pyridine C-Nucleosides. Part One, Nucleosides and Nucleotides, 13:10, 2345-2366, DOI:
10.1080/15257779408013225
To link to this article: http://dx.doi.org/10.1080/15257779408013225
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