
Tetrahedron p. 4819 - 4828 (1995)
Update date:2022-08-04
Topics:
Black, David St. C.
Horsham, Mark A.
Rose, Michael
A linear synthesis, a convergent synthesis and cyclic Mannich reactions were used to prepare the macrocyclic bispidinone ionophores (6-7), (14) and (12-13). The convergent synthesis required successful alkylation of the N-unsubstituted bispidinone (9).
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