Synthesis of new macrocyclic bispidinone ionophores

DOI: 10.1016/0040-4020(95)00161-Z

Source and publish data:

Tetrahedron p. 4819 - 4828 (1995)

Update date:2022-08-04

Topics:

Authors:

Black, David St. C.

Horsham, Mark A.

Rose, Michael

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Article abstract of DOI:10.1016/0040-4020(95)00161-Z

A linear synthesis, a convergent synthesis and cyclic Mannich reactions were used to prepare the macrocyclic bispidinone ionophores (6-7), (14) and (12-13). The convergent synthesis required successful alkylation of the N-unsubstituted bispidinone (9).

Full text of DOI:10.1016/0040-4020(95)00161-Z

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Product name:3,7-bis(2-hydroxybenzyl)-1,5-diphenyl-3,7-diazabicyclo<3.3.1>nonan-9-one

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