A new class of chiral modifiers for the enantioselective hydrogenation of α-ketoesters with Pt/Al2O3

DOI: 10.1016/0957-4166(95)00034-M

Source and publish data:

Tetrahedron Asymmetry p. 505 - 518 (1995)

Update date:2022-07-29

Topics:

Authors:

Simons Simons

Wang Wang

Heinz Heinz

Giger Giger

Mallat Mallat

Pfaltz Pfaltz

Baiker Baiker

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00034-M

A series of enantiomerically pure chiral amino alcohols have been synthesized and applied as modifiers in the enantioselective hydrogenation of ethyl pyruvate over supported Pt catalysts. Their use enabled an enantiomeric excess of up to 75%. A molecular modelling study of the modifiers and reactant on a Pt(111) surface provides explanation for the observed enantiodifferentiation.

Full text of DOI:10.1016/0957-4166(95)00034-M

Products guided by the article

Product name:1,2-Ethanediol, 1-(1-naphthalenyl)-, 2-(4-methylbenzenesulfonate), (R)-

Cas No:16726-92-4

R&D Labs maybe for 16726-92-4

Taizhou volsen chemical Co., Ltd

website:http://www.volsenchem.com

Contact:+86-576-88869393

Address:Jiaojiang District, Taizhou, Zhejiang, China.
Tianjin Jingye Fine Chemicals Co., Ltd.

Contact:+86-15722078107; +86-22-26911407

Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
Pale Palm Imex

Contact:+36(21)2523420

Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
spr oncocare pvt ltd

Contact:91 Area80 9844218056

Address:
enantiotech corporation ltd

Contact:+86-0760-85282375

Address:zhongjing road,zhongshan torch hi-tech industrial development zone

Relevant to this article

Synthesis of 3-fluoroazetidines

Doi:10.1021/jo061095b
(2006)
Improved process for the preparation of montelukast: Development of an efficient synthesis, identification of critical impurities and degradants

Doi:10.1021/op900311z
(2010)
Synthesis, antimicrobial and antiviral evaluation of certain thienopyrimidine derivatives

Doi:10.1016/0223-5234(96)88255-9
(1995)
Synthesis of highly functionalized propargylic alcohols: Direct addition of epoxy acetylides to aldehydes and ketones

Doi:10.1002/1522-2675(200210)85:10<3176::AID-HLCA3176>3.0.CO;2-7
(2002)
Investigation of RuO₂-IrO₂-SnO₂ thin film evolution: A thermoanalytical and spectroscopic study

Doi:10.1007/s10973-006-7578-2
(2006)
Doi:10.1016/0040-4020(68)89045-3
(1968)

Article Doi