Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids

Article abstract of DOI:10.1021/jm00015a004

Retinoids elicit biological responses by activating a series of nuclear receptors. Six retinoid receptors belonging to two families are currently known: retinoic acid receptors (RAR(α,β,andγ)) and retinoid X receptors (RXR(α,β,andγ)). Stilbene retinoid an