Structure-reactivity relationships as probes for the inhibition mechanism of cholesterol esterase by aryl carbamates. I. Steady-state kinetics

Article abstract of DOI:10.1002/jccs.200000066

For substituted phenyl-N-butyl carbamates (1) and 4-nitrophenyl-N-substituted carbamates (2), linear relationships between values of NH proton chemical shift (δ_NH), pKa, and logk_[OH] and Hammett substituent constant (σ) or Taft subst