Synthesis of I-125 labeled photoaffinity rapamycin analogs

DOI: 10.1002/(SICI)1099-1344(199603)38:3<227::AID-JLCR837>3.0.CO;2-1

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 227 - 237 (1996)

Update date:2022-07-31

Topics:

Authors:

Shu, Arthur Y.L.

Yamashita, Dennis S.

Holt, Dennis A.

Heys, J. Richard

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Article abstract of DOI:10.1002/(SICI)1099-1344(199603)38:3<227::AID-JLCR837>3.0.CO;2-1

Two no-carrier-added ¹²⁵I-labeled photoaffinity rapamycin analogs were prepared: 7-demethoxy-7-(4-azido-3-¹²⁵I-benzyloxy)rapamycin (2) and its C₂₈-C₂₉ seco analog 3. The key reactions of the synthesis were subst

Full text of DOI:10.1002/(SICI)1099-1344(199603)38:3<227::AID-JLCR837>3.0.CO;2-1

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