Pesticidal Activities of Some 3-Aryl-4-methylpyrazolobenzodiazepines and 4-Aryl-2-imino-5-methyl-1,3-thiazinobenzodiazepines

Article abstract of DOI:10.1021/jf00058a032

A number of 3-aryl-4-methylpyrazolo<3,4-b><1,5>benzodiazepines and 4-aryl-2-amino-5-methyl-1,3-thiazino<4,5-b><1,5>benzodiazepines have been synthesized from 3-(arylmethylene)-4-methyl-1,5-benzodiazepin-2-one by cyclocondensation with hydrazine hydrate and thiourea in basic medium, respectively.All of the compounds were evaluated for their insecticidal and fungistatic activities, and the results are compared with the standard insecticide Propoxure and the standard fungicide Maneb.Some structure-activity relationships are discussed on the basis of screening data. - Keywords: Pyrazolo<3,4-b><1,5>benzodiazepines; thiazino<4,5-b><1,5>benzodiazepines; insecticidal and fungistatic activities