Pyrrolopyrimidine Folate Analogues: "Inverted" Analogues of the Cytotoxic Agent LY231514

DOI: 10.1021/jo00129a040

Source and publish data:

Journal of Organic Chemistry p. 7947 - 7952 (1995)

Update date:2022-08-02

Topics:

Authors:

Taylor, Edward C.

Young, Wendy B.

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Article abstract of DOI:10.1021/jo00129a040

N-<4-<2-(2-Amino-4(3H)-oxo-5H-pyrrolo<3,2-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamic acid (3a) and N-<4-<3-(2-amino-4(3H)-oxo-5H-pyrrolo<3,2-d>pyrimidin-5-yl)propyl>benzoyl>-L-glutamic acid (3b) were synthesized as potential anticancer agents.

Full text of DOI:10.1021/jo00129a040

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