Stereoselective Synthesis of Novel Methylene Ether Dipeptide Isosteres

DOI: 10.1016/0040-4039(95)00712-L

Source and publish data:

Tetrahedron Letters p. 4151 - 4154 (1995)

Update date:2022-08-03

Topics:

Authors:

Norman, Bryan H.

Kroin, Julian S.

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Article abstract of DOI:10.1016/0040-4039(95)00712-L

We have developed a versatile new synthesis of the Ψ pseudopeptides from N-protected 5-substituted morpholin-3-ones.This approach focuses on a stereoselective alkylation of the morpholin-3-ones.The resulting alkylation products were used in the synt

Full text of DOI:10.1016/0040-4039(95)00712-L

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Product name:(S)-5-isobutyl-4-(4-methoxybenzyl)morpholin-3-one

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