Tetrahedron Asymmetry p. 617 - 620 (1993)
Update date:2022-08-03
Topics:
Alajarin, Ramon
Alvarez-Builla, Julio
Vaguero, Juan J.
Sunkel, Carlos
Casa-Juana, Miguel Fau de
et al.
The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (furnidipine), have been synthesized and separated by chiral chromatography using D-phenylglycine as chiral stationary phase.Enantiomeric purity of stereoisomers is determined by HPLC-CSP technique and configurations deduced via X-ray crystallography.
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