Tetrahedron Letters p. 6957 - 6960 (1995)
Update date:2022-08-04
Topics:
Szeto, Peter
Lathbury, David C.
Gallagher, Timothy
A synthesis of lactam 2, which constitutes a formal total synthesis of (-)-slaframine 1, is described with key steps being (a) intramolecular aldol reaction of ketoaldehyde 4 to establish the indolizidine framework and (b) diastereoselective reduction of enone 5 using the Corey oxazaborolidine 7.
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Doi:10.1039/jr9530000192
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(2019)Doi:10.1007/BF00477447
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