Characterization and application of a new diprotected cyclam: A novel two-step synthesis of linked tetraazamacrocycles

DOI: 10.1016/0040-4039(95)00931-2

Source and publish data:

Tetrahedron Letters p. 4995 - 4998 (1995)

Update date:2022-08-02

Topics:

Authors:

Boitrel, Bernard

Andrioletti, Bruno

Lachkar, Mohammed

Guilard, Roger

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Article abstract of DOI:10.1016/0040-4039(95)00931-2

The synthesis and separation of the 1,8-di-(tertbutyloxycarbonyl) cyclam (1,8-diboc cyclam) among other isomers allow the facile obtention of singly or doubly linked, and bridged tetraazamacrocycles within a two-step synthesis in a very convenient way. This strategy can be applied to a large scale preparation of several types of dioxygen carriers or activators.

Full text of DOI:10.1016/0040-4039(95)00931-2

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