Synthesis of some oxadiazole derivatives of D-mannose

Article abstract of DOI:10.1002/jhet.5570320322

The syntheses of 2-methyl-5-[1',2',3',4',5'-penta-O-benzoyl-D-manno-pentitol-1'-yl]-1,3 ,4-oxadiazole and 5-methyl-3-[1',2',3',4',5'-penta-O-benzoyl-D-manno-pentitol-1'-yl]-1,2 ,4-oxadiazole, as well as their intermediate products, are described. Their ¹H and ¹³C nmr and ms spectra are presented and their preferential conformation in solution are proposed.