Archiv der Pharmazie p. 505 - 516 (1995)
Update date:2022-07-29
Topics:
Frohberg
Kupfer
Stenger
Baumeister
Nuhn
α-Carbonyl carboxylic acid arylhydrazonochlorides obtained by Japp-Klingemann reaction are the starting substances for the synthesis of α-carbonyl carboxylic acid arylhydrazonoamides, -esters and -thioesters. The inhibiting activity of these compounds against 15- and 5-lipoxygenase is described. Reactions of derivatives of amidrazones with formaldehyde give triazole, triazoline and unexpected benzotriazepine derivatives.
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(1995)
