
Chemical and Pharmaceutical Bulletin p. 1081 - 1088 (1995)
Update date:2022-08-06
Topics:
Nagasaka
Imai
The following chiral pyrrolidine derivatives, 7-substituted (2R,5S)-2- aryl-1-aza-3-oxabicyclo[3.3.0]octan-8-ones (18-24), 7-substituted (2R,5S)-2- aryl-1-aza-3-oxabicyclo[3.3.0]oct-6-en-8-ones (25-29) and 3-substituted (S)- 5-(hydroxymethyl)-2-pyrrolidinones (30-34), were synthesized starting from (S)-pyroglutamic acid and their absolute configurations were determined based on their 1H-NMR spectra.
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Doi:10.1039/c39950002033
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