Synthesis and amination of 5- and 8-amino derivatives of 2-phenylnaphtho-1,3-thiazole-4,9-dione

Article abstract of DOI:10.1007/BF00700175

5- and 8-Amino-2-phenylnaphtho<2,3-d>-1,3-thiazole-4,9-diones were obtained by treatment of 3,5-diamino-2-chloro- and 2,5-diamino-3-chloro-1,4-naphthoquinones with sodium sulfide followed by condensation with benzaldehyde.Thermal and photochemical butylamination and CoCl2-promoted arylation of 5-amino-2-phenylnaphthothiazole-4,9-dione in position 8 was carried out. - Key words: 1,4-naphthoquinone; 5- and 8-amino-2-phenyl-naphtho<2,3-d>-1,3-thiazole-4,9-dione; heteroannelation; direct amination; photoamination.