Synthesis of functionalised 2'-C-branched nucleosides via their γ-butyrolactones

DOI: 10.1016/0040-4039(95)01226-8

Source and publish data:

Tetrahedron Letters p. 6341 - 6344 (1995)

Update date:2022-08-03

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Authors:

Lawrence

Pavey Pavey

O'Neil O'Neil

Cosstick

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Article abstract of DOI:10.1016/0040-4039(95)01226-8

Functionalised 2'-C-branched nucleosides that contain either a carboxylic acid (2), a primary amide (3) or a primary hydroxyl (4) group have been prepared and their protection for oligonucleotide synthesis investigated. The 2'-C-3'-O-γ-butyrolactone (5) w

Full text of DOI:10.1016/0040-4039(95)01226-8

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Product name:5'-O-Dimethoxytrityluridine 2'-deoxy-2'-α-C,3'-O-γ-butyrolactone

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