Design and synthesis of a novel epoxide-containing pyrrolo[2,1-c[]1,4]benzodiazepine (PBD) via a new cyclization procedure

DOI: 10.1016/0040-4039(95)01224-6

Source and publish data:

Tetrahedron Letters p. 6333 - 6336 (1995)

Update date:2022-07-30

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Authors:

Wilson Wilson

Howard Howard

Thurston

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Article abstract of DOI:10.1016/0040-4039(95)01224-6

The synthesis of a potential DNA-crosslinking pyrrolo[2,1-c]-[1,4]benzodiazepine (PBD) substituted at the C8-position with a 2,3-epoxypropaneoxy moiety using a new cyclization procedure is described.

Full text of DOI:10.1016/0040-4039(95)01224-6

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