Asymmetric Nitrone-Vinyl Sulfoxide Cycloadditions: a Highly Enantioselective Synthesis of (+)-Sedridine

DOI: 10.1016/0957-4166(95)00287-Y

Source and publish data:

Tetrahedron Asymmetry p. 2149 - 2152 (1995)

Update date:2022-08-03

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Authors:

Louis, Chantal

Hootele, Claude

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Article abstract of DOI:10.1016/0957-4166(95)00287-Y

Cycloaddition of 2,3,4,5-tetrahydropyridine-1-oxide 1 to (Z)-(R)-vinyl sulfoxides 2a-d proceeds in high yield to give isoxazolidines 3a-d and 4a-d with complete exo selectivity and with 82-98percent asymmetric induction.This method provides an efficient s

Full text of DOI:10.1016/0957-4166(95)00287-Y

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