Tetrahedron Letters p. 3131 - 3134 (1997)
Update date:2022-08-05
Topics:
Ku, Thomas W.
Ali, Fadia E.
Bondinell, William E.
Erhard, Karl F.
Huffmann, William F.
et al.
An alternate enantiospecific synthesis of methyl (S)-7-tert-butoxycarbonyl-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetate (5) is reported.The key step, which involves an intermolecular displacement of the activated aryl fluoride (9) by L-aspartic acid β-mehtyl ester, proceeds without racemization.
View MoreContact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Contact:+86-519-86623222
Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
Zhejiang Sanmei Chemical Industry Co., Ltd
Contact:86-579-87633213
Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Contact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Suzhou Time-chem Technologies Co., Ltd.
Contact:0512-63983931/68086856
Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
Doi:10.1021/jo00135a035
(1982)Doi:10.1016/S0040-4039(00)87262-7
(1982)Doi:10.1016/j.tetlet.2020.152483
(2020)Doi:10.1002/jlac.198219820420
(1982)Doi:10.1021/ic048987j
(2004)Doi:10.1248/cpb.30.534
(1982)
