Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]- quinoxaline-2,3-dione and related quinoxalinediones: Characterization of α- amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D- aspartate) receptor and anticonvulsant activ

DOI: 10.1021/jm00019a003

Source and publish data:

Journal of Medicinal Chemistry p. 3720 - 3740 (1995)

Update date:2022-08-04

Topics:

Authors:

Bigge Bigge

Malone Malone

Boxer Boxer

Nelson Nelson

Ortwine Ortwine

Schelkun

Retz Retz

Lescosky

Borosky Borosky

Vartanian

Schwarz Schwarz

Campbell

Robichaud

Watjen Watjen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00019a003

Four related series of substituted quinoxalinediones containing angular fused-piperidine rings have been synthesized as α-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid (AMPA) receptor antagonists with potential as neuroprotective agents, primarily f

Full text of DOI:10.1021/jm00019a003

Products guided by the article

Product name:5-bromo-2-(1-methylpropyl)-1,2,3,4-tetrahydro-8-nitroisoquinoline

Cas No:171619-73-1

R&D Labs maybe for 171619-73-1

zhouxinguo

Contact:15122693241

Address:Tianjin Huanyu Group import and export Inc ，NO.3 Yunnan Road，Tianjin，China
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province
Shanghai Dianyang Industry Co.,ltd

Contact:+86 21 6492 4669

Address:Chejing RD, Songjiang District, Shanghai, China
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)

Contact:86 512 57910558

Address:qianjin M road

Relevant to this article

Fluorination of methyl 6-deoxy-1-thiohexopyranosides with diethylaminosulfur trifluoride (DAST), and the formation of unexpected products

Doi:10.1016/0008-6215(93)84076-I
(1993)
Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

Doi:10.1021/jo00129a037
(1995)
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin

Doi:10.1021/acs.jmedchem.0c01809
(2021)
Convenient synthesis of N1-substituted orotic acid derivatives

Doi:10.1016/j.tetlet.2014.10.005
(2014)
A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors

Doi:10.1021/jm00023a007
(1995)
Synthesis of Tn and Sialyl Tn Building Blocks for Solid Phase Glycopeptide Synthesis

Doi:10.1016/0040-4039(95)01515-9
(1995)

Article Doi