Journal of the American Chemical Society p. 11055 - 11059 (1995)
Update date:2022-08-05
Topics:
Miyashita, Kazuyuki
Massova, Irina
Taibi, Pascale
Mobashery, Shahriar
The design, synthesis, and evaluation of 6α-(hydroxymethyl)penicillanic acid (4) as a new mechanism-based inhibitor for the class A TEM-1 β-lactamase is described. The design of this compound was aided by computer modeling, using the high-resolution cryst
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Doi:10.1071/CH9951587
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