Tetrahedron Letters p. 6879 - 6882 (1995)
Update date:2022-08-02
Topics:
Wendeborn, Sebastian
Wolf, Romain M.
De Mesmaeker, Alain
The two olefinic backbone replacements III and IV were synthesized and incorporated into oligonucleotides. The hybridization properties of the modified oligonucleotides to DNA and RNA complements and conformational analyses of III and IV are compared to the corresponding amide modifications I and II.
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