Synthesis of polyamide nucleic acids (PNAs) using a novel Fmoc/Mmt protecting-group combination

DOI: 10.1016/0960-894X(96)00082-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 665 - 670 (1996)

Update date:2022-08-03

Topics:

Authors:

Breipohl

Knolle Knolle

Langner Langner

O'Malley

Uhlmann Uhlmann

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Article abstract of DOI:10.1016/0960-894X(96)00082-0

The preparation of 9-Fluorenylmethoxycarbonyl(Fmoc) protected building blocks for the synthesis of polyamide nucleic acids (PNAs) is described. Use of 4-Methoxyphenyldiphenylmethyl (Mmt)-protecting groups for the exocyclic amino function of the nucleobase

Full text of DOI:10.1016/0960-894X(96)00082-0

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