Attempted Enantioselective Synthesis of Terbutaline. Unexpected Partial Racemization During Lithium Aluminium Hydride Reduction of a Secondary Amide

DOI: 10.1071/CH9951741

Source and publish data:

Australian Journal of Chemistry p. 1741 - 1746 (1995)

Update date:2022-08-03

Topics:

Authors:

Donohue, Andrew C.

Jackson, W. Roy

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Article abstract of DOI:10.1071/CH9951741

Syntheses leading to compounds related to the brobchodilator (-)-terbutaline via optically active cyanohydrins suffered unexpected partial racemization during lithium aluminium hydride reduction of key amide intermediates.

Full text of DOI:10.1071/CH9951741

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