Palladium catalysis in the synthesis of 8-position modified adenosine, 2'- deoxyadenosine and guanosine

Article abstract of DOI:10.1080/15257779508009745

Adenosine and guanosine analogs with 8-position vinyl and aryl groups were prepared by palladium catalyzed cross-coupling of organostannanes with 8- bromopurine nucleosides. The reaction conditions and catalyst composition were improved so that both vinyl

Full text of DOI:10.1080/15257779508009745

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Nucleosides and Nucleotides
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Palladium Catalysis in the Synthesis
of 8-Position modified Adenosine, 2′-
Deoxyadenosine and Guanosine
Chi Tu a , Charlene Keane a & Bruce E. Eaton a
a Medicinal Chemistry Department Nexagen, Inc. , 2860 Wilderness
Place, Boulder, CO, 80301
Published online: 24 Sep 2006.
To cite this article: Chi Tu , Charlene Keane & Bruce E. Eaton (1995) Palladium Catalysis in the
Synthesis of 8-Position modified Adenosine, 2′-Deoxyadenosine and Guanosine, Nucleosides and
Nucleotides, 14:8, 1631-1638, DOI: 10.1080/15257779508009745
To link to this article: http://dx.doi.org/10.1080/15257779508009745
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