New cyclohexyl-based chiral auxiliaries: Enantioselective synthesis of α-hydroxy acids

DOI: 10.1016/0040-4020(95)00771-Y

Source and publish data:

Tetrahedron p. 12169 - 12178 (1995)

Update date:2022-07-30

Topics:

Authors:

Basavaiah, Deevi

Krishna, Peddinti Rama

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00771-Y

(1R,2R)-2-(4-tert-butylphenoxy) cyclohexan-1-ol (5) and (1R,2R)-2-(4-phenylphenoxy) cyclohexan-1-ol (6) have been used for the first time as chiral auxiliaries. Addition of alkylzinc chlorides to the corresponding glyoxylates 5a, 6a, after hydrolysis, provided (R)-α-hydroxy acids in high optical purities.

Full text of DOI:10.1016/0040-4020(95)00771-Y

Products guided by the article

Product name:<(1R,2R)-2-(4-phenylphenoxy)cyclohexan-1-yl> phenylglyoxylate

Cas No:173031-14-6

R&D Labs maybe for 173031-14-6

Jinan Baozhao Pharmaceutical Co., Ltd

Contact:0086-531-86397156 82371858 82371868

Address:Huaneng Road, Jinan, Shandong ,China
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Hubei Xinghuo Chemical Co., Ltd.,

Contact:13925817279 13907299441

Address:Xinghuo Fine Chemistry Industrial Park, Xiaochang County, Hubei Province, China
Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China

Relevant to this article

Chiral non-racemic bis(vicinal 1,2-diamines): 4,5-diamino-N-(3,4-diaminobutyl)pentanamide tetrahydrochloride, N,N'-bis[3,4-bis(t-butoxycarbonylamino)butyl]urea and N,N'-bis[3,4-bis(t-butoxycarbonylamino)butyl]hexanamide

Doi:10.1016/0040-4020(95)00853-Z
(1995)
Visible-Light-Induced Regioselective Cyanomethylation of Imidazopyridines and Its Application in Drug Synthesis

Doi:10.1021/acs.joc.7b00750
(2017)
The synthesis of palladium-gold and platinum-gold bimetallic complexes ased upon bis(diphenylarsino)methane: Crystal structure of trans-[Pd(μ-Ph₂AsCH₂AsPh₂AuCl) ₂Cl₂]·xCH₂Cl₂

Doi:10.1016/0277-5387(95)00294-3
(1996)
Behaviour of Stereoisomeric O-Methyltyrosyl-p-nitrophenylalanines within the β-Cyclodextrin Cavity

Doi:10.1039/c39950002437
(1995)
3-pyridylethanolamines: Potent and selective human β₃ adrenergic receptor agonists

Doi:10.1016/S0960-894X(98)00571-X
(1998)
Efficient Synthesis of Aminonaphthoquinones and Azidobenzohydroquinones: Mechanistic Considerations of the Reaction of Hydrazoic Acid with Quinones. An Overview

Doi:10.1021/jo9614708
(1997)

Article Doi