Tetrahedron Letters p. 8387 - 8390 (1995)
Update date:2022-09-26
Topics:
Zhang, Lin-hua
Meier, W.
Wats, E.
Costello, T. D.
Ma, P.
et al.
Traditional syntheses of benzodiazepines involve a Bischler-Napieralski reaction which is a three step process and gives low overall yields.An attractive alternative is to construct the diazepine ring under Pictet-Spengler conditions.This paper reports the synthesis of a novel pyridoindolobenzodiazepine as a potent atypical antipsychotic agent.The key step in the synthesis is the ring formation of the diazepine ring in neat trifluoroacetic acid.
View MoreNanjing Maycrop Chemical Co.,Ltd
Contact:86-15345189349
Address:BUILDING 3,DEYING INTERNATIONAL PLAZA,NO.222 CHANGHONG ROAD,YUHUATAI,NANJING,CHINA
Xinjiang Fufeng Biotechnologies Co., Ltd.
Contact:+86-539-7287111
Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
FREEBARQUE DEVELOPMENT GROUP LIMITED
Contact:+86(0)10-5109 5335 or 5109 5345
Address:Room602,Block1-B,LINGDI OFFICE,NO.13 BEIYUAN ROAD
Changzhou Hopschain Chemical Co.,Ltd
website:http://www.hopschem.cn/products.html
Contact:86-519-85528066
Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Tangshan Wisdom Trading Co.,Ltd
Contact:86 315 2222979
Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
Doi:10.1021/ja01641a001
(1954)Doi:10.1016/0040-4020(96)00034-8
(1996)Doi:10.1021/op700218j
(2008)Doi:10.1016/S0968-0896(98)00148-5
(1998)Doi:10.1135/cccc19961037
(1996)Doi:10.1016/0020-1693(96)05027-X
(1996)
