A Facile Access to Peptides Containing D-α-Methyl β-Alkylserines by Coupling of α-Branched Leuchs Anhydrides with α-Amino Esters

DOI: 10.1039/c39950002327

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 2327 - 2328 (1995)

Update date:2022-08-03

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Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Urchegui, Raquel

Garcia, Jesus M.

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Article abstract of DOI:10.1039/c39950002327

A new one step synthesis of α,α-disubstituted α-amino acid N-carboxy anhydrides from α-hydroxy β-lactams and their coupling with α-aminoesters promoted by KCN is described.

Full text of DOI:10.1039/c39950002327

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