Tetrahedron Letters p. 5745 - 5748 (1999)
Update date:2022-09-26
Topics:
Kigoshi, Hideo
Kanematsu, Kengo
Uemura, Daisuke
Bioassay-guided separation of the aqueous ethanol extract of the viscera of the Japanese gastropod Turbo marmorata resulted in the isolation of two toxins, turbotoxins A and B. The structures were determined by spectral analysis and confirmed by organic synthesis to be diiodotyramine derivatives. Turbotoxins A and B exhibited acute toxicity against ddY mice, with LD99 values of 1.0 and 4.0 mg/kg, respectively.
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