Pyran derivatives XX. 2-Aminochromone benzo-fused derivatives with antiproliferative properties

Article abstract of DOI:10.1016/S0014-827X(98)00055-X

The N-substituted 2-aminochromones 1 and their benzo-fused derivatives 2-4 described herein were mostly prepared by treating the corresponding (methylthio) derivatives 10-13 with an excess of the proper amines. Only the morpholino derivatives 3d and 4c we