Mechanistic studies on thiaminase I. 1. The stereochemical course of the reaction

DOI: 10.1006/bioo.1995.1036

Source and publish data:

Bioorganic Chemistry p. 512 - 518 (1995)

Update date:2022-08-04

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Authors:

Nicewonger

Rammelsberg

Costello

Begley Begley

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Article abstract of DOI:10.1006/bioo.1995.1036

Thiaminase I catalyzes the displacement of the thiazole moiety of thiamin by a wide variety of nucleophiles. In this paper, we demonstrate that this reaction proceeds with overall retention of stereochemistry.

Full text of DOI:10.1006/bioo.1995.1036

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