Mechanistic studies on thiaminase I. 1. The stereochemical course of the reaction

DOI: 10.1006/bioo.1995.1036

Source and publish data:

Bioorganic Chemistry p. 512 - 518 (1995)

Update date:2022-08-04

Topics:

Authors:

Nicewonger

Rammelsberg

Costello

Begley Begley

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1006/bioo.1995.1036

Thiaminase I catalyzes the displacement of the thiazole moiety of thiamin by a wide variety of nucleophiles. In this paper, we demonstrate that this reaction proceeds with overall retention of stereochemistry.

Full text of DOI:10.1006/bioo.1995.1036

Products guided by the article

Product name:4-amino-5-(S)-hydroxydeuteriomethyl-2-methylpyrimidinyl-(4-nitrobenzoate)

Cas No:173557-77-2

R&D Labs maybe for 173557-77-2

Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
shanghai tuomiao chemicial co.,ltd.

website:https://www.tuomiaochem.com/

Contact:021 - 59853336

Address:shanghai
ALPHA PHARMACEUTICAL CO，LTD JIANGSU

Contact:+86-527-84829968,+86-527-84829998

Address:suqian city
Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.

Relevant to this article

Doi:10.1007/BF01172549
()
One-pot inter- and intramolecular Friedel-Crafts reactions in Baylis-Hillman chemistry: A novel facile synthesis of (E)-2-arylideneindan-1-ones

Doi:10.1016/S0040-4039(01)00354-9
(2001)
Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant

Doi:10.1021/jm00108a003
(1991)
Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2

Doi:10.1021/jm4004895
(2013)
Ring opening/C-N cyclization of activated aziridines with carbon nucleophiles: Highly diastereo- and enantioselective synthesis of tetrahydroquinolines

Doi:10.1021/ol2016077
(2011)
Solvent-dependent supramolecular assemblies of π-conjugated anion-responsive acyclic oligopyrroles

Doi:10.1039/c1cc12827b
(2011)

Article Doi