Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant

DOI: 10.1021/jm00108a003

Source and publish data:

Journal of Medicinal Chemistry p. 1253 - 1257 (1991)

Update date:2022-08-04

Topics:

Authors:

Robertson

Beedle Beedle

Krushinski

Lawson Lawson

Parli Parli

Potts Potts

Leander Leander

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Article abstract of DOI:10.1021/jm00108a003

The 4-aminobenzamides have provided several anticonvulsants that have been extensively investigated. Ameltolide, 4-amino-N-(2,6-dimethylphenyl)benzamide (compound 2, LY201116), is the most potent analogue studied to date. This drug is inactivated in vivo

Full text of DOI:10.1021/jm00108a003

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