7-Alkyl-7-hydroxymethyl-3,4-dimethoxynorcaradienes: A new type of norcaradiene stabilized by π-donors

DOI: 10.1016/0040-4039(95)01882-I

Source and publish data:

Tetrahedron Letters p. 8817 - 8820 (1995)

Update date:2022-08-04

Topics:

Authors:

Matsumoto, Masakatsu

Shiono, Tamaki

Kasuga, Noriko C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01882-I

Introduction of an alkyl (aralkyl) substituent at the 7-position of 7-ethoxycarbonyl-3,4-dimethoxynorcaradiene (7a) gives fairly stable norcaradienes (NCD) (7b-f). The reduction products (8b-f) of NCD (7b-f) exist mainly as NCD form especially at low temperature, although 8b-f no longer possess any π-acceptor at the 7-position. The present results clarify that two methoxyl groups as the π donors at the 3,4-position stabilize the NCD structure.

Full text of DOI:10.1016/0040-4039(95)01882-I

Products guided by the article

Product name:(7-Benzyl-3,4-dimethoxy-bicyclo[4.1.0]hepta-2,4-dien-7-yl)-methanol

Cas No:173673-79-5

R&D Labs maybe for 173673-79-5

Zhengzhou Institute of Chiral Pharmer Research Co., Ltd.

Contact:86-371-55219111

Address:15 Floor, 2 Building, Central China Technovalley, Zhongyuan West Road
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
SuZhou Yacoo Science Co., Ltd

website:https://www.yacoo.com.cn/en/

Contact:86-512-87182055

Address:No.112 Xinqing Rd, Suzhou Industrial Park, China, 215125, China

Relevant to this article

Kinetics and Mechanism of the Formation and Acid Dissociation of Cobalt(II), Nickel(II), and Copper(II) Complexes with the Highly Enolized β-Diketone 3-(N-Acetylamido)pentane-2,4-dione (=Hamac) in Aqueous Solution

Doi:10.1021/ic950272g
(1996)
Synthesis of Aromatic Derivatives of 1,5-Benzodiazepine in the Reaction of 4-Nitro-o-phenylenediamine with Chalcone Dibromides

Doi:10.1007/BF01170744
(1995)
Synthesis of pseudonucleosides containing chiral sulfahydantoins as aglycone (II)

Doi:10.1016/0040-4020(95)00932-9
(1996)
A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

Doi:10.1016/0040-4039(95)02237-6
(1996)
Optically active antifungal azoles. IX. An alternative synthetic route for 2-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol- 1-yl)propyl]-4-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-3(2H,4H)1,2,4- triazolone and its analogs

Doi:10.1248/cpb.47.360
(1999)
A convenient approach to diastereomerically pure 1,3,4-trisubstituted pyrrolidin-2-ones by intramolecular cyclisation of N-(2-alken-1-yl)amides mediated by Mn(III). An entry to both (R)- and (S)-3-pyrrolidineacetic acid

Doi:10.1016/0040-4020(95)00939-6
(1996)

Article Doi