Synthesis of Optically Active 2',3'-Dideoxy-3'-oxa-4'-thio-ribonucleoside Analogues by Transposition of a Leaving Group on Chiral Oxathiolanes via a Reductive-oxidative Process

DOI: 10.1016/S0040-4039(00)76955-3

Source and publish data:

Tetrahedron Letters p. 4739 - 4742 (1994)

Update date:2022-09-26

Topics:

Authors:

Wang, Wei

Jin, Haolun

Mansour, Tarek S.

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Article abstract of DOI:10.1016/S0040-4039(00)76955-3

The synthesis of chiral nucleoside analogues with a unique structural feature is reported.The strategy is based on a reductive-oxidative process to complete the transposition of the leaving group in chiral oxathiolanes with known configuration.

Full text of DOI:10.1016/S0040-4039(00)76955-3

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