Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives

DOI: 10.1248/cpb.47.1694

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Chemical and Pharmaceutical Bulletin p. 1694 - 1712 (1999)

Update date:2022-08-04

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Authors:

Ono, Shin'ichiro

Yoshida, Tomohiro

Maeda, Kazuhiro

Kosaka, Keigo

Inoue, Yoshihisa

Imada, Teruaki

Fukaya, Chikara

Nakamura, Norifumi

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Article abstract of DOI:10.1248/cpb.47.1694

A novel series of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists with condensed heterocycles as their basic core was synthesized. In an in vitro assay, trans-4-(5-amidinobenzofuran-2- carboxamido)cyclohexyl]oxyacetic acid 17e and trans-3-[4-(5-

Full text of DOI:10.1248/cpb.47.1694

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