2-Arylmethyl-1,4-benzoquinones. I. Novel inhibitors of platelet aggregation: Synthesis and pharmacological evaluation

DOI: 10.1248/cpb.44.139

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 139 - 144 (1996)

Update date:2022-07-30

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Authors:

Suzuki, Kenji

Tatsuoka, Toshio

Murakami, Tomiko

Ishihara, Takafumi

Aisaka, Kazuo

Inoue, Teruyoshi

Ogino, Ryoko

Kuroki, Manami

Miyazaki, Tomoko

Satoh, Fumio

Miyano, Seiji

Sumoto, Kunihiro

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Article abstract of DOI:10.1248/cpb.44.139

A new series of 2-arylmethyl-1,4-benzoquinones (2) was synthesized for evaluation of their pharmacological activities. These compounds showed significant inhibition of platelet aggregation induced by arachidonic acid (AA) and some of them possessed a prot

Full text of DOI:10.1248/cpb.44.139

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