
Tetrahedron p. 2629 - 2646 (1996)
Update date:2022-07-31
Topics:
Louwrier, Saskia
Tuynman, Antonin
Hiemstra, Henk
The syntheses of three bicyclic guanidines as model compounds for the guanidine alkaloid ptilomycalin A are described. The guanidines are prepared from pyrrolidin-2-one via an N-acyliminium ion coupling reaction with silyl enol ethers and a direct guanylation with bis-Boc-thiourea and HgCl2 as the key steps.
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Doi:10.1016/0022-1139(95)03338-6
(1996)Doi:10.1039/c7nj03999a
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