Phosphonic acid and phosphinic acid tripeptides as inhibitors of glutathionylspermidine synthetase

DOI: 10.1016/0960-894X(96)00001-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 253 - 258 (1996)

Update date:2022-08-02

Topics:

Authors:

Verbruggen, Christophe

De Craecker, Sofie

Rajan, Padinchare

Jiao, Xian-Yun

Borloo, Marianne

Smith, Keith

Fairlamb, Alan H.

Haemers, Achiel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00001-7

A series of phosphonic and phosphinic acid derivatives of glutathione were synthesized as potential inhibitors of glutathionylspermidine synthetase, an essential enzyme in the biosynthesis of trypanothione in trypanosomatids. The compounds showed moderate activity. Copyright

Full text of DOI:10.1016/0960-894X(96)00001-7

Products guided by the article

Product name:diethyl 3-dibenzylamino-2-hydroxypropylphosphonate

Cas No:175027-94-8

R&D Labs maybe for 175027-94-8

Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD
Jiangxi Province Bethel Pharmaceutical Co., Ltd.

Contact:+86-795-259 3456 ，+86-15957688008 13566650571

Address:Huangjindui Chemical Park， Shanggao County ，Yichun city，Jiangxi Province
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Shanghai PuYi Chem-Tech Co.,Ltd.

Contact:+86-21-57687505-227

Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China

Relevant to this article

Synthesis of constrained 4-(phosphonomethyl)phenylalanine derivatives as hydrolytically stable analogs of O-phosphotyrosine

Doi:10.1016/0040-4020(96)00085-3
(1996)
The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

Doi:10.1016/0040-4039(96)00324-3
(1996)
Chemistry of polyfunctional molecules. 119: Tetracarbonyl-dicobalt-tetrahedrane complexes with the ligands Bis(diphenylphosphanyl)-amine, 2-butin-1,4-diol, and tert.-butylphosphaacetylene - Crystal structure of the phosphaalkyne derivative

Doi:10.1002/zaac.19966220214
(1996)
Studies on the intramolecular cycloaddition reaction of isomunchnones derived from N-alkenyl substituted diazoimides

Doi:10.1016/0040-4020(95)01108-0
(1996)
Doi:10.1021/ja01469a040
(1961)
Synthesis of 3-(2-Guanidinoethyl) and 3-[2-(S-Methylisothioureidoethyl)] Analogs of 5-Isopropyl 2,6-Dimethyl-1,4-dihydro-4-(2,3-dichlorophenyl) pyridine-3,5-dicarboxylate as a Respective Releaser of Nitric Oxide and Inhibitor of Nitric Oxide Synthase

Doi:10.1002/jhet.5570330127
(1996)

Article Doi