Phosphonic acid and phosphinic acid tripeptides as inhibitors of glutathionylspermidine synthetase

DOI: 10.1016/0960-894X(96)00001-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 253 - 258 (1996)

Update date:2022-08-02

Topics:

Authors:

Verbruggen, Christophe

De Craecker, Sofie

Rajan, Padinchare

Jiao, Xian-Yun

Borloo, Marianne

Smith, Keith

Fairlamb, Alan H.

Haemers, Achiel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00001-7

A series of phosphonic and phosphinic acid derivatives of glutathione were synthesized as potential inhibitors of glutathionylspermidine synthetase, an essential enzyme in the biosynthesis of trypanothione in trypanosomatids. The compounds showed moderate activity. Copyright

Full text of DOI:10.1016/0960-894X(96)00001-7

Products guided by the article

Product name:diethyl 3-dibenzylamino-2-hydroxypropylphosphonate

Cas No:175027-94-8

R&D Labs maybe for 175027-94-8

Afine Chemicals Limited

website:http://www.afinechem.com

Contact:+86-571-85134551

Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
Nanjing distinctions Medical Technology Co., Ltd.(expird)

Contact:+86-15996203785 13914714059

Address:nanjing,jiangsu , China
Shanghai Maxchemco Chemical Industry Co., Ltd.

Contact:(86)21-51079223

Address:No.1305-8, B241, the Ecust Park, Huajing Road, Xuhui District, Shanghai
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-39971718

Address:859 jiadingchengliu shanghai

Relevant to this article

Synthesis of constrained 4-(phosphonomethyl)phenylalanine derivatives as hydrolytically stable analogs of O-phosphotyrosine

Doi:10.1016/0040-4020(96)00085-3
(1996)
The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

Doi:10.1016/0040-4039(96)00324-3
(1996)
Chemistry of polyfunctional molecules. 119: Tetracarbonyl-dicobalt-tetrahedrane complexes with the ligands Bis(diphenylphosphanyl)-amine, 2-butin-1,4-diol, and tert.-butylphosphaacetylene - Crystal structure of the phosphaalkyne derivative

Doi:10.1002/zaac.19966220214
(1996)
Studies on the intramolecular cycloaddition reaction of isomunchnones derived from N-alkenyl substituted diazoimides

Doi:10.1016/0040-4020(95)01108-0
(1996)
Doi:10.1021/ja01469a040
(1961)
Synthesis of 3-(2-Guanidinoethyl) and 3-[2-(S-Methylisothioureidoethyl)] Analogs of 5-Isopropyl 2,6-Dimethyl-1,4-dihydro-4-(2,3-dichlorophenyl) pyridine-3,5-dicarboxylate as a Respective Releaser of Nitric Oxide and Inhibitor of Nitric Oxide Synthase

Doi:10.1002/jhet.5570330127
(1996)

Article Doi