Bioorganic and Medicinal Chemistry Letters p. 319 - 322 (1998)
Update date:2022-08-05
Topics:
Vaccaro, Wayne D.
Sher, Rosy
Davis Jr., Harry R.
Metabolism initiated SAR studies led to the discovery of a new class of potent 2-azetidinone cholesterol absorption inhibitors. These studies found that a heteroatom at the para position of the C-4 phenyl ring is not a requirement for cholesterol absorption inhibition as was suggested by earlier findings. Substitution of Ph-linker-COOR for PhOMe at the C-4 position enhanced absorption inhibition.
View MoreZhejiang Linhai Xinhua Chemicals Factory
Contact:0086-13661858911
Address:Xunqiao Development Zone, Linhai, Zhejiang, China
NINGBO PANGS CHEM INT’L CO.,LTD.
Contact:+86-574-27666845
Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA
Shanghai Yuking Water Soluble Material Tech Co., Ltd
Contact:86-21-68286299
Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Contact:+86-519-86623222
Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
taicang liyuan chemical co,.ltd
website:http://www.tcliyuanchem.com/productse.php
Contact:86-512-53539583
Address:Room 804,Huaxu Building,No.95,Renmin South Road,Taicang city,Jiangsu Province,China
Doi:10.1021/jo9601369
(1996)Doi:10.1021/ja01126a015
(1952)Doi:10.1139/v67-418
(1967)Doi:10.1016/0022-328X(95)05976-V
(1996)Doi:10.1016/0022-328X(95)05969-V
(1996)Doi:10.1021/jo960033q
(1996)
