Bioorganic and Medicinal Chemistry Letters p. 385 - 390 (1996)
Update date:2022-07-29
Topics:
Babine, Robert E.
Bleckman
Littlefield, Ethel S.
Parge, Hans E.
Pelletier
Lewis, Cristina T.
French, Judy V.
Imbacuan, Michael
Katoh, Susumo
Tatlock, John H.
Showalter, Richard E.
Villafranca, J. Ernest
The design, synthesis, and structure activity relationships of a series of novel macrocyclic FKBP-12 ligands 1 are reported. The crystal structure of the complex between 7 and human FKBP-12 is reported and some SAR results are discussed based on this complex.
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Doi:10.1007/bf01169961
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(2003)Doi:10.1021/jm9604080
(1996)Doi:10.1021/jp014659i
(2002)Doi:10.1016/S0040-4039(00)89878-0
(1968)
