Stereoselective enzymatic hydrolysis of dimethyl meso-piperidine-3,5-dicarboxylates

DOI: 10.1016/0957-4166(96)00002-X

Source and publish data:

Tetrahedron Asymmetry p. 345 - 348 (1996)

Update date:2022-07-31

Topics:

Authors:

Danieli, Bruno

Lesma, Giordano

Passarella, Daniele

Silvani, Alessandra

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Article abstract of DOI:10.1016/0957-4166(96)00002-X

Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), lipase from Candida cylindracea (CCL) and porcine pancreatic lipase (PPL) is described. The enantioselectivities of the enzymatic transformations and the absolute configurations of the resulting half-esters 2a-c were determined.

Full text of DOI:10.1016/0957-4166(96)00002-X

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Product name:(3R,5S)-Piperidine-1,3,5-tricarboxylic acid 1-benzyl ester 3-methyl ester

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