Chemical and Pharmaceutical Bulletin p. 602 - 604 (1996)
Update date:2022-07-31
Topics:
Kameo, Kazuya
Takeshita, Kimiyo
Yasuda, Yoshiko
Matsumoto, Keita
Tomisawa, Kazuyuki
2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanonic acid (KE-298) is an antirheumatic agent. To elucidate the effects of optically active KE-298, we resolved the racemic acid and obtained the two optical isomers. ( + )-KE-298 was converted to the 4-bromo
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(1996)
