Use of cyclohexene epoxides in the preparation of carbocyclic nucleosides

Article abstract of DOI:10.1080/07328319608002133

A simple route towards 4,4-dihydroxymethyl-cyclohexane nucleosides has been developed. The structure of 4,4-dihydroxymethyl-1-(thymin-1-yl)- cyclohexane was confirmed by X-ray analysis. The synthesized compounds were inactive against all viruses tested.

Full text of DOI:10.1080/07328319608002133

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Nucleosides and Nucleotides
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Use of Cyclohexene Epoxides in the
Preparation of Carbocyclic Nucleosides
S. N. Mikhailov a , N. Blaton a , J. Rozenski a , J. Balzarini a , E.
De Clercq a & P. Herdewijn a
a Rega Institute for Medical Research and Pharmaceutical
Institute , Katholieke Universiteit Leuven , Minderbroedersstraat
10, Leuven, B-3000, Belgium
Published online: 20 Aug 2006.
To cite this article: S. N. Mikhailov , N. Blaton , J. Rozenski , J. Balzarini , E. De Clercq & P.
Herdewijn (1996) Use of Cyclohexene Epoxides in the Preparation of Carbocyclic Nucleosides,
Nucleosides and Nucleotides, 15:4, 867-878, DOI: 10.1080/07328319608002133
To link to this article: http://dx.doi.org/10.1080/07328319608002133
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